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51

Transcriptional priming of intrathymic precursors for dendritic cell development

Moore, A. J., Sarmiento, J., Mohtashami, M., Braunstein, M., Zuniga-Pflucker, J.-C., Anderson, M. K.

Journal:

Development (The Company of Biologists)

Year:

2013

Language:

english

File:

PDF, 73 KB

english, 2013

52

GATA-3 regulates the self-renewal of long-term hematopoietic stem cells

Frelin, Catherine, Herrington, Robert, Janmohamed, Salima, Barbara, Mary, Tran, Gary, Paige, Christopher J, Benveniste, Patricia, Zuñiga-Pflücker, Juan-Carlos, Souabni, Abdallah, Busslinger, Meinrad,

Journal:

Nature Immunology

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

53

T Lymphocyte Potential Marks the Emergence of Definitive Hematopoietic Progenitors in Human Pluripotent Stem Cell Differentiation Cultures

Kennedy, Marion, Awong, Geneve, Sturgeon, Christopher M., Ditadi, Andrea, LaMotte-Mohs, Ross, Zúñiga-Pflücker, Juan Carlos, Keller, Gordon

Journal:

Year:

2012

Language:

english

File:

PDF, 2.56 MB

english, 2012

54

Zoned Out: Functional Mapping of Stromal Signaling Microenvironments in the Thymus

Petrie, Howard T., Zúñiga-Pflücker, Juan Carlos

Journal:

Annual Review of Immunology

Year:

2007

Language:

english

File:

PDF, 566 KB

english, 2007

55

Adapting in vitro embryonic stem cell differentiation to the study of locus control regions

Lahiji, Armin, Kučerová-Levisohn, Martina, Holmes, Roxanne, Zúñiga-Pflücker, Juan Carlos, Ortiz, Benjamin D.

Journal:

Journal of Immunological Methods

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

56

The orphan nuclear receptor Ear-2 (Nr2f6) is a novel negative regulator of T cell development

Ichim, Christine V., Dervović, Džana D., Zúñiga-Pflücker, Juan Carlos, Wells, Richard A.

Journal:

Experimental Hematology

Year:

2014

Language:

english

File:

PDF, 4.18 MB

english, 2014

57

Controlled generation of hematopoietic progenitor cells from pluripotent stem cells using microenvironmental cues

Rahman, Muhammad, Brauer, Patrick, Zúñiga-Pflücker, Juan, Zandstra, Peter

Journal:

Experimental Hematology

Year:

2013

Language:

english

File:

PDF, 46 KB

english, 2013

58

Precursor thymocytes follow AN IL-2/IL-2 receptor-dependent pathway of differentiation

Zúñiga-Pflücker, J.C., Kruisbeek, A.M.

Journal:

Research in Immunology

Year:

1990

Language:

english

File:

PDF, 641 KB

english, 1990

59

Functional Characterization of B Lymphocytes Generated in vitro from Embryonic Stem Cells

Sarah K. Cho, Travis D. Webber, James R. Carlyle, Toru Nakano, Susanna M. Lewis and Juan Carlos Zúñiga-Pflücker

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.41 MB

english, 1999

60

FOXN1GFP/w Reporter hESCs Enable Identification of Integrin-β4, HLA-DR, and EpCAM as Markers of Human PSC-Derived FOXN1+ Thymic Epithelial Progenitors

Soh, Chew-Li, Giudice, Antonietta, Jenny, Robert A., Elliott, David A., Hatzistavrou, Tanya, Micallef, Suzanne J., Kianizad, Korosh, Seach, Natalie, Zúñiga-Pflücker, Juan Carlos, Chidgey, Ann P., Trou

Journal:

Stem Cell Reports

Year:

2014

Language:

english

File:

PDF, 3.04 MB

english, 2014

61

The Thymus as an Inductive Site for T Lymphopoiesis

Ciofani, Maria, Zúñiga-Pflücker, Juan Carlos

Journal:

Annual Review of Cell and Developmental Biology

Year:

2007

Language:

english

File:

PDF, 381 KB

english, 2007

62

An Overview of the Intrathymic Intricacies of T Cell Development

Shah, D. K., Zuniga-Pflucker, J. C.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 949 KB

english, 2014

63

An in vitro model of innate lymphoid cell function and differentiation

Allan, D SJ, Kirkham, C L, Aguilar, O A, Qu, L C, Chen, P, Fine, J H, Serra, P, Awong, G, Gommerman, J L, Zúñiga-Pflücker, J C, Carlyle, J R

Journal:

Mucosal Immunology

Year:

2015

Language:

english

File:

PDF, 2.93 MB

english, 2015

64

T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis

Critchfield, J., Racke, M., Zuniga-Pflucker, J., Cannella, B, Raine, C., Goverman, J, Lenardo, M.

Journal:

Year:

1994

Language:

english

File:

PDF, 1.76 MB

english, 1994

65

Notch signals are required for in vitro but not in vivo maintenance of human hematopoietic stem cells and delay the appearance of multipotent progenitors

Benveniste, P., Serra, P., Dervovic, D., Herer, E., Knowles, G., Mohtashami, M., Zuniga-Pflucker, J. C.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.06 MB

english, 2014

66

When Three Negatives Made a Positive Influence in Defining Four Early Steps in T Cell Development

Zuniga-Pflucker, J. C.

Journal:

The Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 856 KB

english, 2012

67

Duration and Strength of Extracellular Signal-Regulated Kinase Signals Are Altered During Positive Versus Negative Thymocyte Selection

Mariathasan, S., Zakarian, A., Bouchard, D., Michie, A. M., Zuniga-Pflucker, J. C., Ohashi, P. S.

Journal:

The Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 507 KB

english, 2001

68

A Monoclonal Antibody Against the Extracellular Domain of Mouse and Human Epithelial V-like Antigen 1 Reveals a Restricted Expression Pattern Among CD4- CD8- Thymocytes

Garabatos, Nahir, Blanco, Jesus, Fandos, Cesar, Lopez, Elena, Santamaria, Pere, Ruiz, Andrea, Perez-Vidakovics, Maria Laura, Benveniste, Patricia, Galkin, Oleksandr, Zuñiga-Pflucker, Juan Carlos, Serr

Journal:

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

Year:

2014

Language:

english

File:

PDF, 389 KB

english, 2014

69

Dedicated mTEC Progenitors Stay True, Even into Adulthood

Kianizad, Korosh, Zúñiga-Pflücker, Juan Carlos

Journal:

Year:

2014

Language:

english

File:

PDF, 311 KB

english, 2014

70

Noncanonical Mode of ERK Action Controls Alternative αβ and γδ T Cell Lineage Fates

Lee, Sang-Yun, Coffey, Francis, Fahl, Shawn P., Peri, Suraj, Rhodes, Michele, Cai, Kathy Q., Carleton, Michael, Hedrick, Stephen M., Fehling, Hans Joerg, Zúñiga-Pflücker, Juan Carlos, Kappes, Dietmar

Journal:

Year:

2014

Language:

english

File:

PDF, 3.78 MB

english, 2014

71

Comparative and Functional Evaluation of In Vitro Generated to Ex Vivo CD8 T Cells

Dervovic, D. D., Ciofani, M., Kianizad, K., Zuniga-Pflucker, J. C.

Journal:

The Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 1.27 MB

english, 2012

72

Competitive Displacement of pT by TCR- During TCR Assembly Prevents Surface Coexpression of Pre-TCR and TCR

Trop, S., Rhodes, M., Wiest, D. L., Hugo, P., Zuniga-Pflucker, J. C.

Journal:

The Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 1.12 MB

english, 2000

73

A Natural Structural Variant of the Mouse TCR -Chain Displays Intrinsic Receptor Function and Antigen Specificity

Aublin, A., Ciofani, M., Willkomm, N., Hamrouni, A., Szymczak-Workman, A. L., Takahashi, T., Sandjeu, Y., Guillaume, P., Vignali, D. A. A., Michielin, O., Zuniga-Pflucker, J. C., Maryanski, J. L.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 928 KB

english, 2006

74

Propensity of Adult Lymphoid Progenitors to Progress to DN2/3 Stage Thymocytes with Notch Receptor Ligation

Huang, J., Garrett, K. P., Pelayo, R., Zuniga-Pflucker, J. C., Petrie, H. T., Kincade, P. W.

Journal:

The Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 938 KB

english, 2005

75

TLR Ligand-Induced Type I IFNs Affect Thymopoiesis

Baron, M.-L., Gauchat, D., La Motte-Mohs, R., Kettaf, N., Abdallah, A., Michiels, T., Zuniga-Pflucker, J.-C., Sekaly, R.-P.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 1.50 MB

english, 2008

76

Notch Signaling Requires GATA-2 to Inhibit Myelopoiesis from Embryonic Stem Cells and Primary Hemopoietic Progenitors

de Pooter, R. F., Schmitt, T. M., de la Pompa, J. L., Fujiwara, Y., Orkin, S. H., Zuniga-Pflucker, J. C.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 787 KB

english, 2006

77

Cyclic Adenosine 5'-Monophosphate Response Element Binding Protein Plays a Central Role in Mediating Proliferation and Differentiation Downstream of the Pre-TCR Complex in Developing Thymocytes

Grady, G. C., Mason, S. M., Stephen, J., Zuniga-Pflucker, J. C., Michie, A. M.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 411 KB

english, 2004

78

Complete TCR- Gene Locus Control Region Activity in T Cells Derived In Vitro from Embryonic Stem Cells

Lahiji, A., Kucerova-Levisohn, M., Lovett, J., Holmes, R., Zuniga-Pflucker, J. C., Ortiz, B. D.

Journal:

The Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

79

Low Activation Threshold As a Mechanism for Ligand-Independent Signaling in Pre-T Cells

Haks, M. C., Belkowski, S. M., Ciofani, M., Rhodes, M., Lefebvre, J. M., Trop, S., Hugo, P., Zuniga-Pflucker, J. C., Wiest, D. L.

Journal:

The Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 505 KB

english, 2003

80

Clonal Characterization of a Bipotent T Cell and NK Cell Progenitor in the Mouse Fetal Thymus

Michie, A. M., Carlyle, J. R., Schmitt, T. M., Ljutic, B., Cho, S. K., Fong, Q., Zuniga-Pflucker, J. C.

Journal:

The Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 558 KB

english, 2000

81

The role of nuclear factor- B essential modulator (NEMO) in B cell development and survival

Kim, S., La Motte-Mohs, R. N. A., Rudolph, D., Zuniga-Pflucker, J. C., Mak, T. W.

Journal:

Proceedings of the National Academy of Sciences

Year:

2003

Language:

english

File:

PDF, 527 KB

english, 2003

82

The Original Intrathymic Progenitor from Which T Cells Originate

Zuniga-Pflucker, J. C.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 965 KB

english, 2009

83

Obligatory Role for Cooperative Signaling by Pre-TCR and Notch during Thymocyte Differentiation

Ciofani, M., Schmitt, T. M., Ciofani, A., Michie, A. M., Cuburu, N., Aublin, A., Maryanski, J. L., Zuniga-Pflucker, J. C.

Journal:

The Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 387 KB

english, 2004

84

New role identified for LRR-containing proteins in T cell development

Zuniga-Pflucker, J.-C.

Journal:

Journal of Experimental Medicine

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

85

The Stress Kinase Mitogen-Activated Protein Kinase Kinase (Mkk)7 Is a Negative Regulator of Antigen Receptor and Growth Factor Receptor-Induced Proliferation in Hematopoietic Cells

Sasaki, T., Wada, T., Kishimoto, H., Irie-Sasaki, J., Matsumoto, G., Goto, T., Yao, Z., Wakeham, A., Mak, T. W., Suzuki, A., Cho, S. K., Zuniga-Pflucker, J. C., Oliveira-dos-Santos, A. J., Katada, T.,

Journal:

Journal of Experimental Medicine

Year:

2001

Language:

english

File:

PDF, 237 KB

english, 2001

86

Functional characterization of B lymphocytes generated in vitro from embryonic stem cells

Cho, S. K., Webber, T. D., Carlyle, J. R., Nakano, T., Lewis, S. M., Zuniga-Pflucker, J. C.

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 208 KB

english, 1999

87

Identification of Upstream cis-Acting Regulatory Elements Controlling Lineage-specific Expression of the Mouse NK Cell Activation Receptor, NKR-P1C

Ljutic, B., Carlyle, J. R., Zuniga-Pflucker, J. C.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 470 KB

english, 2003

88

Sublethal gamma-radiation induces differentiation of CD4-/CD8- into CD4+/CD8+ thymocytes without T cell receptor beta rearrangement in recombinase activation gene 2-/- mice

Zuniga-Pflucker, J. C.

Journal:

Journal of Experimental Medicine

Year:

1994

Language:

english

File:

PDF, 566 KB

english, 1994

89

CD8 is required during positive selection of CD4-/CD8+ T cells

Zuniga-Pflucker, J. C.

Journal:

Journal of Experimental Medicine

Year:

1990

Language:

english

File:

PDF, 862 KB

english, 1990

90

The Basic Helix-Loop-Helix Transcription Factor HEBAlt Is Expressed in Pro-T Cells and Enhances the Generation of T Cell Precursors

Wang, D., Claus, C. L., Vaccarelli, G., Braunstein, M., Schmitt, T. M., Zuniga-Pflucker, J. C., Rothenberg, E. V., Anderson, M. K.

Journal:

The Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 1.68 MB

english, 2006

91

Identification of a Novel Developmental Stage Marking Lineage Commitment of Progenitor Thymocytes

Carlyle, J. R., Michie, A. M., Furlonger, C., Nakano, T., Lenardo, M. J., Paige, C. J., Zuniga-Pflucker, J. C.

Journal:

Journal of Experimental Medicine

Year:

1997

Language:

english

File:

PDF, 259 KB

english, 1997

92

Leukocyte Infiltration and Activation of the NLRP3 Inflammasome in White Adipose Tissue Following Thermal Injury*

Stanojcic, Mile, Chen, Peter, Harrison, Rachael A., Wang, Vivian, Antonyshyn, Jeremy, Zúñiga-Pflücker, Juan Carlos, Jeschke, Marc G.

Journal:

Critical Care Medicine

Year:

2014

Language:

english

File:

PDF, 679 KB

english, 2014

93

Hematopoiesis: from start to immune reconstitution potential

Liang, Haydn C-Y, Zúñiga-Pflücker, Juan Carlos

Journal:

Stem Cell Research & Therapy

Year:

2015

Language:

english

File:

PDF, 857 KB

english, 2015

94

Direct Comparison of Dll1- and Dll4-Mediated Notch Activation Levels Shows Differential Lymphomyeloid Lineage Commitment Outcomes

Mohtashami, M., Shah, D. K., Nakase, H., Kianizad, K., Petrie, H. T., Zuniga-Pflucker, J. C.

Journal:

The Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 2.00 MB

english, 2010

95

The TCR ligand-inducible expression of CD73 marks lineage commitment and a metastable intermediate in effector specification

Coffey, F., Lee, S.-Y., Buus, T. B., Lauritsen, J.-P. H., Wong, G. W., Joachims, M. L., Thompson, L. F., Zuniga-Pflucker, J. C., Kappes, D. J., Wiest, D. L.

Journal:

Journal of Experimental Medicine

Year:

2014

Language:

english

File:

PDF, 2.27 MB

english, 2014

96

Dynamics of Human Prothymocytes and Xenogeneic Thymopoiesis in Hematopoietic Stem Cell-Engrafted Nonobese Diabetic-SCID/IL-2r null Mice

Parietti, V., Nelson, E., Telliam, G., Le Noir, S., Pla, M., Delord, M., Vanneaux, V., Mohtashami, M., Macintyre, E. A., Gluckman, J. C., Asnafi, V., Zuniga-Pflucker, J.-C., Larghero, J., Canque, B.

Journal:

The Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 3.47 MB

english, 2012

97

Role of CD4 in thymocyte selection and maturation

Zuniga-Pflucker, J. C.

Journal:

Journal of Experimental Medicine

Year:

1989

Language:

english

File:

PDF, 873 KB

english, 1989

98

T cell development runs marrow deep

Zuniga-Pflucker, J. C.

Journal:

Journal of Experimental Medicine

Year:

2015

Language:

english

File:

PDF, 2.02 MB

english, 2015

99

Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors

Chen, N.-J., Chio, I. I. C., Lin, W.-J., Duncan, G., Chau, H., Katz, D., Huang, H.-L., Pike, K. A., Hao, Z., Su, Y.-W., Yamamoto, K., de Pooter, R. F., Zuniga-Pflucker, J. C., Wakeham, A., Yeh, W.-C.,

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 1.15 MB

english, 2008

100

Enforcement of -lineage commitment by the pre-T-cell receptor in precursors with weak -TCR signals

Zarin, P., Wong, G. W., Mohtashami, M., Wiest, D. L., Zuniga-Pflucker, J. C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 938 KB

english, 2014