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1

Carmat Bioprosthetic Total Artificial Heart is Associated With An Early Hemostatic Recovery and No Acquired Willebrand Syndrome in Calves

Smadja, David M., Susen, Sophie, Rauch, Antoine, Cholley, Bernard, Latrémouille, Christian, Duveau, Daniel, Zilberstein, Luca, Méléard, Denis, Boughenou, Marie-Fazia, Belle, Eric Van, Gaussem, Pascale

Journal:

Journal of Cardiothoracic and Vascular Anesthesia

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

2

Evidence that MRP4 is Only Partly Involved in S1P Secretion during Platelet Activation

Decouture, Benoit, Becker, Pierre-Hadrien, Therond, Patrice, Gaussem, Pascale, Bachelot-Loza, Christilla

Journal:

Thrombosis and Haemostasis

Year:

2018

Language:

english

File:

PDF, 91 KB

english, 2018

3

Bone-marrow-derived very small embryonic-like stem cells in patients with critical leg ischaemia: evidence of vasculogenic potential

Guerin, Coralie L., Loyer, Xavier, Vilar, José, Cras, Audrey, Mirault, Tristan, Gaussem, Pascale, Silvestre, Jean-Sébastien, Smadja, David M.

Journal:

Thrombosis and Haemostasis

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

4

Modified ROTEM for the detection of rivaroxaban and apixaban anticoagulant activity in whole blood

Pailleret, Claire, Jourdi, Georges, Siguret, Virginie, Gouin-Thibault, Isabelle, Gandrille, Sophie, Stepanian, Alain, Curis, Emmanuel, Golmard, Jean-Louis, Gaussem, Pascale, Le Bonniec, Bernard, Samam

Journal:

European Journal of Anaesthesiology

Year:

2018

Language:

english

File:

PDF, 790 KB

english, 2018

5

Rivaroxaban pharmacodynamics in healthy volunteers evaluated with thrombin generation and the active protein C system: modeling and assessing inter-individual variability

Siguret, Virginie, Abdoul, Johan, Delavenne, Xavier, Curis, Emmanuel, Carlo, Audrey, Blanchard, Anne, Salem, Joe-Elie, Gaussem, Pascale, Funck-Brentano, Christian, Azizi, Michel, Mismetti, Patrick, Lo

Journal:

Journal of Thrombosis and Haemostasis

Year:

2019

Language:

english

File:

PDF, 640 KB

english, 2019

6

Endothelial progenitor cells are selectively mobilised immediately after coronary artery bypass grafting or valve surgery

Smadja, David, Godier, Anne, Susen, Sophie, Packard, René, Fabiani, Jean-Noël, Aiach, Martine, Gaussem, Pascale

Journal:

Thrombosis and Haemostasis

Year:

2009

File:

PDF, 71 KB

2009

7

Platelet Functions During Extracorporeal Membrane Oxygenation. PlateletâLeukocyte Aggregates Analyzed by Flow Cytometry as a Promising Tool to Monitor Platelet Activation

Mansour, Alexandre, Roussel, Mikael, Gaussem, Pascale, NÃ©delec-Gac, Fabienne, Pontis, Adeline, FlÃ©cher, Erwan, Bachelot-Loza, Christilla, Gouin-Thibault, Isabelle

Journal:

Journal of Clinical Medicine

Year:

2020

File:

PDF, 1.57 MB

2020

8

Serum antibodies to distinct epitopes of the tissue-type plasminogen activator (t-PA) in patients with systemic lupus erythematosus

Alejandro Ruiz-Arguelles, Eduardo Angles-Cano, Beatriz Perez-Romano, Guillermo J. Ruiz-Arguelles, Margarita Deleze, Donato Alarcon-Segovia, Pascale Gaussem

Journal:

American Journal of Hematology

Year:

1995

Language:

english

File:

PDF, 586 KB

english, 1995

9

Comparison of Endothelial Biomarkers According to Reversibility of Pulmonary Hypertension Secondary to Congenital Heart Disease

David M. Smadja, Pascale Gaussem, Laetitia Mauge, Romaric Lacroix, Sophie Gandrille, Véronique Remones, Séverine Peyrard, Florence Sabatier, Damien Bonnet, Marilyne Lévy

Journal:

Pediatric Cardiology

Year:

2010

Language:

english

File:

PDF, 198 KB

english, 2010

10

Treprostinil increases the number and angiogenic potential of endothelial progenitor cells in children with pulmonary hypertension

David M. Smadja, Laetitia Mauge, Pascale Gaussem, Clément d’Audigier, Dominique Israel-Biet, David S. Celermajer, Damien Bonnet, Marilyne Lévy

Journal:

Year:

2011

Language:

english

File:

PDF, 468 KB

english, 2011

11

Platelet receptor gain-of-function single nucleotide polymorphisms in carotid and vertebral stenosis patients

Andrea Kopp Lugli, Martin M. Brown, Jan Steffel, Linda Büchi, Dorothee Förnzler, Annabelle Dupont, Pascale Gaussem, Marc Forestier, Juerg H. Beer

Journal:

Journal of Thrombosis and Thrombolysis

Year:

2011

Language:

english

File:

PDF, 276 KB

english, 2011

12

Bone marrow-derived mononuclear cell therapy induces distal angiogenesis after local injection in critical leg ischemia

Van Huyen, Jean-Paul Duong, Smadja, David M, Bruneval, Patrick, Gaussem, Pascale, Dal-Cortivo, Liliane, Julia, Pierre, Fiessinger, Jean-Noël, Cavazzana-Calvo, Marina, Aiach, Martine, Emmerich, Joseph

Journal:

Modern Pathology

Year:

2008

Language:

english

File:

PDF, 823 KB

english, 2008

13

The formation of complexes between human plasminogen activator inhibitor-1 (PAI-1) and sodium dodecyl sulfate: possible implication in the functional properties of PAI-1

Pascale Gaussem, Eduardo Anglés-Cano

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1991

Language:

english

File:

PDF, 1.05 MB

english, 1991

14

Effect of clopidogrel on circulating biomarkers of angiogenesis and endothelial activation

David M. Smadja, Alessandra Bura, Jean Szymezak, Anne Blanchard, Véronique Remones, Michel Azizi, Pascale Gaussem

Journal:

Journal of Cardiology

Year:

2012

Language:

english

File:

PDF, 359 KB

english, 2012

15

Increased VEGFR2 expression during human late endothelial progenitor cells expansion enhances in vitro angiogenesis with up-regulation of integrin α6

David M. Smadja, Ivan Bièche, Dominique Helley, Ingrid Laurendeau, Ghislaine Simonin, Laurent Muller, Martine Aiach, Pascale Gaussem

Journal:

Journal of Cellular and Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 343 KB

english, 2007

16

Thrombin bound to a fibrin clot confers angiogenic and haemostatic properties on endothelial progenitor cells

David M. Smadja, Agnès Basire, Aymeric Amelot, Aurélie Conte, Ivan Bièche, Bernard F. Le Bonniec, Martine Aiach, Pascale Gaussem

Journal:

Journal of Cellular and Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 390 KB

english, 2008

17

Interleukin 8 is differently expressed and modulated by PAR-1 activation in early and late endothelial progenitor cells

David M. Smadja, Ivan Bièche, Sophie Susen, Laetitia Mauge, Ingrid Laurendeau, Clément D’Audigier, Françoise Grelac, Joseph Emmerich, Martine Aiach, Pascale Gaussem

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

18

No influence of the VAMP8 rs1010 single nucleotide polymorphism on platelet functions in vitro

Pascale Gaussem, Brian Y. Ishida, Pierre Fontana, Clive R. Pullinger, John P. Khane, Martine Aiach, Christilla Bachelot-Loza, Sophie Gandrille

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 970 KB

english, 2009

19

Human thrombin variable region 1, including E39, is involved in interactions with α1-antitrypsin M358R and protein C

Pascale Gaussem, Véronique Picard, Gilliane Chadeuf, Emmanuel Arnaud, Martine Aiach

Journal:

Year:

1995

Language:

english

File:

PDF, 350 KB

english, 1995

20

High on-clopidogrel platelet reactivity: Genotyping Can help to optimize antiplatelet treatment

Jean Szymezak, Caroline Moreau, Marie-Anne Loriot, Eric Durand, Hubert Van Viet, Michel Desnos, Pascale Gaussem

Journal:

Thrombosis Research

Year:

2011

Language:

english

File:

PDF, 417 KB

english, 2011

21

A monoclonal antibody recognizing the activation domain of protein C in its calcium-free conformation

Anne Vincenot, Jean-Louis Pittet, Martine Aiach, Pascale Gaussem

Journal:

Year:

1998

Language:

english

File:

PDF, 147 KB

english, 1998

22

Expression and Characterization of Recombinant Protein S with the Ser 460 Pro Mutation

Olivier Morbœuf, Delphine Borgel, Martine Aiach, Tahar Kaabache, Sophie Gandrille, Pascale Gaussem

Journal:

Thrombosis Research

Year:

2000

Language:

english

File:

PDF, 104 KB

english, 2000

23

Delivery management in a woman with thrombocytopenia of the May–Hegglin anomaly type

Habib Chabane, Yves Gallais, Dominique Pathier, Gil Tchernia, Pascale Gaussem

Journal:

European Journal of Obstetrics & Gynecology and Reproductive Biology

Year:

2001

Language:

english

File:

PDF, 47 KB

english, 2001

24

Purinergic receptor P2Y, G-protein coupled, 12 gene variants and risk of incident ischemic stroke, myocardial infarction, and venous thromboembolism

Robert Y.L. Zee, Sherri E. Michaud, Kirsti A. Diehl, Daniel I. Chasman, Joseph Emmerich, Pascale Gaussem, Martine Aiach, Paul M. Ridker

Journal:

Atherosclerosis

Year:

2008

Language:

english

File:

PDF, 101 KB

english, 2008

25

Endogenous oestradiol as a positive correlate of plasma fibrinogen among older postmenopausal women: a population-based study (the Three-City cohort study)

Canonico, Marianne, Brailly-Tabard, Sylvie, Gaussem, Pascale, Setiao, Julie, Rouaud, Olivier, Ryan, Joanne, Carcaillon, Laure, Guiochon-Mantel, Anne, Scarabin, Pierre-Yves

Journal:

Clinical Endocrinology

Year:

2012

Language:

english

File:

PDF, 153 KB

english, 2012

26

Optimizing the Use of Anticoagulants (Heparins and Oral Anticoagulants) in the Elderly

Siguret, Virginie, Gouin-Thibault, Isabelle, Gaussem, Pascale, Pautas, Eric

Journal:

Year:

2013

Language:

english

File:

PDF, 345 KB

english, 2013

27

Haemorrhagic Complications of Vitamin K Antagonists in the Elderly

Eric Pautas, Isabelle Gouin-Thibault, Matthieu Debray, Pascale Gaussem…

Journal:

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

28

Effects of rabeprazole on the antiplatelet effects and pharmacokinetics of clopidogrel in healthy volunteers

Funck-Brentano, Christian, Szymezak, Jean, Steichen, Olivier, Ducint, Dominique, Molimard, Mathieu, Remones, Véronique, Azizi, Michel, Gaussem, Pascale

Journal:

Archives of Cardiovascular Diseases

Year:

2013

Language:

english

File:

PDF, 1.17 MB

english, 2013

29

Evaluation of recombinant activated factor VII, prothrombin complex concentrate, and fibrinogen concentrate to reverse apixaban in a rabbit model of bleeding and thrombosis

Martin, Anne-Céline, Le Bonniec, Bernard, Fischer, Anne-Marie, Marchand-Leroux, Catherine, Gaussem, Pascale, Samama, Charles-Marc, Godier, Anne

Journal:

International Journal of Cardiology

Year:

2013

Language:

english

File:

PDF, 349 KB

english, 2013

30

Early endothelial progenitor cells in bone marrow are a biomarker of cell therapy success in patients with critical limb ischemia

Smadja, David M., Duong-van-Huyen, Jean-Paul, Dal Cortivo, Liliane, Blanchard, Anne, Bruneval, Patrick, Emmerich, Joseph, Gaussem, Pascale

Journal:

Year:

2012

Language:

english

File:

PDF, 720 KB

english, 2012

31

In Vitro Plasma-Induced Endothelial Oxidative Stress and Circulating Markers of Endothelial Dysfunction in Preeclampsia: An Observational Study

Pottecher, Julien, Huet, Olivier, Degos, Vincent, Bonnet, Marie-Pierre, Gaussem, Pascale, Duranteau, Jacques, Ozier, Yves, Mignon, Alexandre, Tsatsaris, Vassilis

Journal:

Hypertension in Pregnancy

Year:

2009

Language:

english

File:

PDF, 193 KB

english, 2009

32

280: Circulating endothelial cell levels decrease after vasodilator therapy and are a biomarker of deterioration in pediatric pulmonary hypertension

Lévy, Marilyne, Bonnet, Damien, Mauge, Laetitia, D’Audigier, Clément, Szezepanski, Isabelle, Gaussem, Pascale, Smadja, David

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

33

Imbalanced coagulation profile as a biomarker of migraine in children with sickle cell: Is this a link with cerebral ischemia?

Kossorotoff, Manoelle, Lasne, Dominique, Brousse, Valentine, Desguerre, Isabelle, de Montalembert, Mariane, Gaussem, Pascale

Journal:

The Journal of Pediatrics

Year:

2014

Language:

english

File:

PDF, 126 KB

english, 2014

34

Common sequence variations in the P2Y 12 and CYP3A5 genes do not explain the variability in the inhibitory effects of clopidogrel therapy

Smith, Simon M. G., Judge, Heather M., Peters, Gary, Armstrong, Martin, Fontana, Pierre, Gaussem, Pascale, Daly, Martina E., Storey, Robert F.

Journal:

Year:

2006

Language:

english

File:

PDF, 152 KB

english, 2006

35

Evaluation of endothelial damage in sepsis-related ARDS using circulating endothelial cells

Moussa, Mouhamed Djahoum, Santonocito, Cristina, Fagnoul, David, Donadello, Katia, Pradier, Olivier, Gaussem, Pascale, De Backer, Daniel, Vincent, Jean-Louis

Journal:

Intensive Care Medicine

Year:

2015

Language:

english

File:

PDF, 262 KB

english, 2015

36

No clear link between VKORC1 genetic polymorphism and the risk of venous thrombosis or peripheral arterial disease

Smadja, David M., Loriot, Marie-Anne, Hindorff, Lucia A., Mellottee, Lucille, Gaussem, Pascale, Emmerich, Joseph

Journal:

Thrombosis and Haemostasis

Year:

2008

Language:

english

File:

PDF, 489 KB

english, 2008

37

Influence of Genetic Variations on Levels of Inflammatory Markers of Healthy Subjects at Baseline and One Week after Clopidogrel Therapy; Results of a Preliminary Study

Shahabi, Payman, Siest, Gérard, Herbeth, Bernard, Lambert, Daniel, Masson, Christine, Hulot, Jean-Sébastien, Bertil, Sébastien, Gaussem, Pascale, Visvikis-Siest, Sophie

Journal:

International Journal of Molecular Sciences

Year:

2013

Language:

english

File:

PDF, 222 KB

english, 2013

38

Thrombin receptor PAR-1 activation on endothelial progenitor cells enhances chemotaxis-associated genes expression and leukocyte recruitment by a COX-2-dependent mechanism

d’Audigier, Clément, Cochain, Clément, Rossi, Elisa, Guérin, Coralie L., Bièche, Ivan, Blandinières, Adeline, Marsac, Bérengère, Silvestre, Jean-Sébastien, Gaussem, Pascale, Smadja, David M.

Journal:

Year:

2015

Language:

english

File:

PDF, 5.64 MB

english, 2015

39

0260 : Endoglin in adhesion between endothelial and mural cells

Rossi, Elisa, Smadja, David, Boscolo, Elisa, Langa, Carmen, Arevalo, Miguel A., Pericacho, Miguel, Kauskot, Alexandre, Botella, Luisa M., Gaussem, Pascale, Bischoff, Joyce, Lopez-Novoa, Josè-Miguel, B

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2015

Language:

english

File:

PDF, 220 KB

english, 2015

40

0304 : Treprostinil indirectly regulates endothelial colony forming cell angiogenic properties by increasing VEGF-A produced by mesenchymal stem cells

Smadja, David, Levy, Marilyne, Huang, Lan, Rossi, Elisa, Israel-Biet, Dominique, Gaussem, Pascale, Bischoff, Joyce

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2015

Language:

english

File:

PDF, 48 KB

english, 2015

41

Inefficacy of Platelet Transfusion to Reverse Ticagrelor

Godier, Anne, Taylor, Guillaume, Gaussem, Pascale

Journal:

New England Journal of Medicine

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

42

Cerebral haemorrhagic risk in children with sickle-cell disease

Kossorotoff, Manoelle, Brousse, Valentine, Grevent, David, Naggara, Olivier, Brunelle, Francis, Blauwblomme, Thomas, Gaussem, Pascale, Desguerre, Isabelle, De Montalembert, Mariane

Journal:

Developmental Medicine & Child Neurology

Year:

2015

Language:

english

File:

PDF, 294 KB

english, 2015

43

Endoglin regulates mural cell adhesion in the circulatory system

Rossi, Elisa, Smadja, David M., Boscolo, Elisa, Langa, Carmen, Arevalo, Miguel A., Pericacho, Miguel, Gamella-Pozuelo, Luis, Kauskot, Alexandre, Botella, Luisa M., Gaussem, Pascale, Bischoff, Joyce, L

Journal:

Cellular and Molecular Life Sciences

Year:

2016

Language:

english

File:

PDF, 10.51 MB

english, 2016

44

MRP4 (ABCC4) as a potential pharmacologic target for cardiovascular disease

Belleville-Rolland, Tiphaine, Sassi, Yassine, Decouture, Benoit, Dreano, Elise, Hulot, Jean-Sébastien, Gaussem, Pascale, Bachelot-Loza, Christilla

Journal:

Pharmacological Research

Year:

2016

Language:

english

File:

PDF, 831 KB

english, 2016

45

La cytokine fibrogénique TGF-β1 augmente les propriétés angiogéniques des progéniteurs endothéliaux circulants

Evrard, Solène, D’Audigier, Clément, Mauge, Laetitia, Israel-Biet, Dominique, Guerin, Coralie, Bieche, Ivan, Kovacic, Jason, Fischer, Anne-Marie, Gaussem, Pascale, Smadja, David

Journal:

Year:

2015

Language:

french

File:

PDF, 57 KB

french, 2015

46

0130 : Endoglin is a new partner involved in platelet – endothelium interactions: role in microvessel stability?

Rossi, Elisa, Bachelot-Loza, Christilla, Pidard, Dominique, Gaussem, Pascale, Smadja, David, Chassac, Sonia, Pericacho, Miguel, Lopez-Novoa, José M., Langa, Carmen, Gonzalez-Manchon, Consuelo, Bernabe

Journal:

Archives of Cardiovascular Diseases Supplements

Year:

2016

Language:

english

File:

PDF, 50 KB

english, 2016

47

The effectiveness of platelet supplementation for the reversal of ticagrelor-induced inhibition of platelet aggregation

Martin, Anne-Céline, Berndt, Célia, Calmette, Leyla, Philip, Ivan, Decouture, Benoit, Gaussem, Pascale, Gouin-Thibault, Isabelle, Samama, Charles-Marc, Bachelot-Loza, Christilla, Godier, Anne

Journal:

European Journal of Anaesthesiology

Year:

2016

Language:

english

File:

PDF, 296 KB

english, 2016

48

Implication of protein S thrombin-sensitive region with membrane binding via conformational changes in the γ-carboxyglutamic acid-rich domain

BORGEL, Delphine, GAUSSEM, Pascale, GARBAY, Christiane, BACHELOT-LOZA, Christilla, KAABACHE, Tahar, LIU, Wang-Qing, BROHARD-BOHN, Brigitte, LE BONNIEC, Bernard, AIACH, Martine, GANDRILLE, Sophie

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 172 KB

english, 2001

49

Implication of protein S thrombin-sensitive region with membrane binding via conformational changes in the γ-carboxyglutamic acid-rich domain

BORGEL, Delphine, GAUSSEM, Pascale, GARBAY, Christiane, BACHELOT-LOZA, Christilla, KAABACHE, Tahar, LIU, Wang-Qing, BROHARD-BOHN, Brigitte, LE BONNIEC, Bernard, AIACH, Martine, GANDRILLE, Sophie

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 172 KB

english, 2001

50

Impaired thromboxane receptor dimerization reduces signaling efficiency: A potential mechanism for reduced platelet function in vivo

Capra, Valérie, Mauri, Mario, Guzzi, Francesca, Busnelli, Marta, Accomazzo, Maria Rosa, Gaussem, Pascale, Nisar, Shaista P., Mundell, Stuart J., Parenti, Marco, Rovati, G. Enrico

Journal:

Biochemical Pharmacology

Year:

2016

Language:

english

File:

PDF, 2.19 MB

english, 2016