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51

Stress, DNA damage and ageing — an integrative approach

Thomas von Zglinicki, Alexander Bürkle, Thomas B.L. Kirkwood

Journal:

Experimental Gerontology

Year:

2001

Language:

english

File:

PDF, 127 KB

english, 2001

52

BJ fibroblasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection

Mario Lorenz, Gabriele Saretzki, Nicolle Sitte, Susanne Metzkow, Thomas von Zglinicki

Journal:

Free Radical Biology and Medicine

Year:

2001

Language:

english

File:

PDF, 274 KB

english, 2001

53

Accelerated Telomere Shortening in Fibroblasts After Extended Periods of Confluency

Nicolle Sitte, Gabriele Saretzki, Thomas von Zglinicki

Journal:

Free Radical Biology and Medicine

Year:

1998

Language:

english

File:

PDF, 1.19 MB

english, 1998

54

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts

Thomas von Zglinicki, Rita Pilger, Nicolle Sitte

Journal:

Free Radical Biology and Medicine

Year:

2000

Language:

english

File:

PDF, 520 KB

english, 2000

55

Protein oxidation and degradation during proliferative senescence of human MRC-5 fibroblasts

Nicolle Sitte, Katrin Merker, Thomas von Zglinicki, Tilman Grune

Journal:

Free Radical Biology and Medicine

Year:

2000

Language:

english

File:

PDF, 433 KB

english, 2000

56

The effect of late onset, short-term caloric restriction on the core temperature and physical activity in mice

Andrew Golightly, Richard J. Boys, Kerry M. Cameron, Thomas von Zglinicki

Journal:

Journal of the Royal Statistical Society: Series C (Applied Statistics)

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

57

Sustained telomere length in hepatocytes and cholangiocytes with increasing age in normal liver

Suman Verma, Phaedra Tachtatzis, Sue Penrhyn-Lowe, Cinzia Scarpini, Diana Jurk, Thomas Von Zglinicki, Nick Coleman, Graeme J. M. Alexander

Journal:

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

58

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

Thomas von Zglinicki, Gabriele Saretzki, Wolf Döcke, Christian Lotze

Journal:

Experimental Cell Research

Year:

1995

File:

PDF, 756 KB

1995

59

Preferential Accumulation of Single-Stranded Regions in Telomeres of Human Fibroblasts

Simone Petersen, Gabriele Saretzki, Thomas von Zglinicki

Journal:

Experimental Cell Research

Year:

1998

Language:

english

File:

PDF, 299 KB

english, 1998

60

Premature senescence of mesothelial cells is associated with non-telomeric DNA damage

Krzysztof Ksiazek, João F. Passos, Sharon Olijslagers, Gabriele Saretzki, Carmen Martin-Ruiz, Thomas von Zglinicki

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 297 KB

english, 2007

61

Mitochondrial dysfunction is a possible cause of accelerated senescence of mesothelial cells exposed to high glucose

Krzysztof Ksiazek, João F. Passos, Sharon Olijslagers, Thomas von Zglinicki

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 605 KB

english, 2008

62

Telomere length and aging biomarkers in 70-year-olds: the Lothian Birth Cohort 1936

Sarah E. Harris, Carmen Martin-Ruiz, Thomas von Zglinicki, John M. Starr, Ian J. Deary

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 416 KB

english, 2012

63

Immortalisation of human ovarian surface epithelium with telomerase and temperature-senstitive SV40 large T antigen

Barry R Davies, Islay A Steele, Richard J Edmondson, Simon A Zwolinski, Gabriele Saretzki, Thomas von Zglinicki, Michael J O’Hare

Journal:

Experimental Cell Research

Year:

2003

Language:

english

File:

PDF, 738 KB

english, 2003

64

Accelerated telomere shortening in Fanconi anemia fibroblasts – a longitudinal study

Caroline Adelfalk, Mario Lorenz, Violeta Serra, Thomas von Zglinicki, Monica Hirsch-Kauffmann, Manfred Schweiger

Journal:

Year:

2001

Language:

english

File:

PDF, 324 KB

english, 2001

65

Human fibroblasts in vitro senesce with a donor-specific telomere length

Violeta Serra, Thomas von Zglinicki

Journal:

Year:

2002

Language:

english

File:

PDF, 239 KB

english, 2002

66

Telomeres and replicative senescence: is it only length that counts?

Thomas von Zglinicki

Journal:

Year:

2001

Language:

english

File:

PDF, 209 KB

english, 2001

67

hTERT gene dosage correlates with telomerase activity in human lung cancer cell lines

Gabriele Saretzki, Simone Petersen, Iver Petersen, Konrad Kölble, Thomas von Zglinicki

Journal:

Year:

2002

Language:

english

File:

PDF, 617 KB

english, 2002

68

Telomeres, telomerase and the cancer cell: an introduction

Thomas von Zglinicki

Journal:

Year:

2003

Language:

english

File:

PDF, 60 KB

english, 2003

69

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response

Diana Jurk, Chunfang Wang, Satomi Miwa, Mandy Maddick, Viktor Korolchuk, Avgi Tsolou, Efstathios S. Gonos, Christopher Thrasivoulou, M. Jill Saffrey, Kerry Cameron, Thomas von Zglinicki

Journal:

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

70

Mitochondrial Dysfunction and Cell Senescence: Cause or Consequence?

Passos, João F., Zglinicki, Thomas von, Saretzki, Gabriele

Journal:

Rejuvenation Research

Year:

2006

Language:

english

File:

PDF, 89 KB

english, 2006

71

Mitochondrial dysfunction in osteoarthritis is associated with down-regulation of superoxide dismutase 2

Gavriilidis, Christos, Miwa, Satomi, von Zglinicki, Thomas, Taylor, Robert W., Young, David A.

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 308 KB

english, 2013

72

Intracellular water and ionic shifts during growth and ageing of rats

Thomas Von Zglinicki, Martina Bimmler

Journal:

Mechanisms of Ageing and Development

Year:

1987

Language:

english

File:

PDF, 408 KB

english, 1987

73

The measurement of water distribution in frozen specimens

Thomas von Zglinicki

Journal:

Journal of Microscopy

Year:

1991

Language:

english

File:

PDF, 1.15 MB

english, 1991

74

Male mice retain a metabolic memory of improved glucose tolerance induced during adult onset, short-term dietary restriction

Kerry M Cameron, Satomi Miwa, Cornelia Walker, Thomas von Zglinicki

Journal:

Longevity & Healthspan

Year:

2012

Language:

english

File:

PDF, 275 KB

english, 2012

75

Oxygen free radicals in cell senescence: Are they signal transducers?

Passos, João F., Von Zglinicki, Thomas

Journal:

Free Radical Research

Year:

2006

Language:

english

File:

PDF, 111 KB

english, 2006

76

Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old

Collerton, Joanna, Ashok, Deepthi, Martin-Ruiz, Carmen, Pyle, Angela, Hudson, Gavin, Yadegarfar, Mohammad, Davies, Karen, Jagger, Carol, von Zglinicki, Thomas, Kirkwood, Thomas B.L., Chinnery, Patrick

Journal:

Neurobiology of Aging

Year:

2013

Language:

english

File:

PDF, 159 KB

english, 2013

77

Low abundance of the matrix arm of complex I of mice liver mitochondria predicts longevity

Miwa, Satomi, Jow, Howsun, Treumann, Achim, von Zglinicki, Thomas

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

78

Quantitative Röntgenmikroanalyse biologischer Ultradünnschnitte mit Aluminium-Kohle-Aufdampfschichten als Standards

Zglinicki, Thomas Von

Journal:

Acta Histochemica

Year:

1983

Language:

german

File:

PDF, 491 KB

german, 1983

79

Health and disease in 85 year olds: baseline findings from the Newcastle 85+ cohort study

Joanna Collerton, Karen Davies, Carol Jagger, Andrew Kingston, John Bond, Martin P Eccles, Louise A Robinson, Carmen Martin-Ruiz, Thomas von Zglinicki, Oliver F W James and Thomas B L Kirkwood

Journal:

Year:

2010

Language:

english

File:

PDF, 332 KB

english, 2010

80

Inflammation, Telomere Length, and Grip Strength: A 10-year Longitudinal Study

Baylis, Daniel, Ntani, Georgia, Edwards, Mark H., Syddall, Holly E., Bartlett, David B., Dennison, Elaine M., Martin-Ruiz, Carmen, von Zglinicki, Thomas, Kuh, Diana, Lord, Janet M., Aihie Sayer, Avan,

Journal:

Calcified Tissue International

Year:

2014

Language:

english

File:

PDF, 279 KB

english, 2014

81

Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+ Study

Collerton, Joanna, Gautrey, Hannah E., van Otterdijk, Sanne D., Davies, Karen, Martin-Ruiz, Carmen, von Zglinicki, Thomas, Kirkwood, Thomas B. L., Jagger, Carol, Mathers, John C., Strathdee, Gordon

Journal:

Year:

2014

Language:

english

File:

PDF, 409 KB

english, 2014

82

Measuring hydrogen peroxide release from isolated liver mitochondria using Amplex Red: A critical evaluation

Miwa, Satomi, von Zglinicki, Thomas

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2014

Language:

english

File:

PDF, 51 KB

english, 2014

83

Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism

Bennaceur, Karim, Atwill, Mark, Al Zhrany, Nayef, Hoffmann, Jedrzej, Keavney, Bernard, Breault, David, Richardson, Gavin, von Zglinicki, Thomas, Saretzki, Gabriele, Spyridopoulos, Ioakim

Journal:

Atherosclerosis

Year:

2014

Language:

english

File:

PDF, 2.18 MB

english, 2014

84

DNA Damage and Telomere Length in Human T Cells

BARNETT, YVONNE A., BARNETT, CHRISTOPHER R., VON ZGLINICKI, THOMAS

Journal:

Journal of Anti-Aging Medicine

Year:

2000

Language:

english

File:

PDF, 925 KB

english, 2000

85

Relocalized redox-active lysosomal iron is an important mediator of oxidative-stress-induced DNA damage

KURZ, Tino, LEAKE, Alan, von ZGLINICKI, Thomas, BRUNK, Ulf T.

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 193 KB

english, 2004

86

Comparison of senescence-associated miRNAs in primary skin and lung fibroblasts

Holly, Alice C., Grellscheid, Sushma, van de Walle, Pieter, Dolan, David, Pilling, Luke C., Daniels, Darren J., von Zglinicki, Thomas, Ferrucci, Luigi, Melzer, David, Harries, Lorna W.

Journal:

Year:

2015

Language:

english

File:

PDF, 343 KB

english, 2015

87

Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice

Miwa, Satomi, Jow, Howsun, Baty, Karen, Johnson, Amy, Czapiewski, Rafal, Saretzki, Gabriele, Treumann, Achim, von Zglinicki, Thomas

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

88

Telomere Shortening and Haemodialysis

Boxall, Mark C., Goodship, Timothy H.J., Brown, Alison L., Ward, Michael C., von Zglinicki, Thomas

Journal:

Blood Purification

Year:

2006

Language:

english

File:

PDF, 110 KB

english, 2006

89

Biomarkers of healthy ageing: expectations and validation

Martin-Ruiz, Carmen, von Zglinicki, Thomas

Journal:

Proceedings of The Nutrition Society

Year:

2014

Language:

english

File:

PDF, 380 KB

english, 2014

90

Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

Dalle Pezze, Piero, Nelson, Glyn, Otten, Elsje G., Korolchuk, Viktor I., Kirkwood, Thomas B. L., von Zglinicki, Thomas, Shanley, Daryl P., Rzhetsky, Andrey

Journal:

PLoS Computational Biology

Year:

2014

Language:

english

File:

PDF, 6.36 MB

english, 2014

91

Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians

Arai, Yasumichi, Martin-Ruiz, Carmen M., Takayama, Michiyo, Abe, Yukiko, Takebayashi, Toru, Koyasu, Shigeo, Suematsu, Makoto, Hirose, Nobuyoshi, von Zglinicki, Thomas

Journal:

Year:

2015

Language:

english

File:

PDF, 1.51 MB

english, 2015

92

The Role of Telomeres in Etoposide Induced Tumour Cell Death

Jeyapalan, Jessie, Leake, Alan, Ahmed, Shaheda, Saretzki, Gabriele, Tilby, Michael, Zglinicki, Thomas von

Journal:

Year:

2004

Language:

english

File:

PDF, 802 KB

english, 2004

93

Nucleoplasmic LAP2α-Lamin A Complexes Are Required to Maintain a Proliferative State in Human Fibroblasts

Vanja Pekovic, Jens Harborth, Jos L. V. Broers, Frans C. S. Ramaekers, Baziel van Engelen, Martin Lammens, Thomas von Zglinicki, Roland Foisner, Chris Hutchison and Ewa Markiewicz

Journal:

The Journal of Cell Biology

Year:

2007

Language:

english

File:

PDF, 2.38 MB

english, 2007

94

Age-related frailty and its association with biological markers of ageing

Mitnitski, Arnold, Collerton, Joanna, Martin-Ruiz, Carmen, Jagger, Carol, von Zglinicki, Thomas, Rockwood, Kenneth, Kirkwood, Thomas B. L.

Journal:

Year:

2015

Language:

english

File:

PDF, 771 KB

english, 2015

95

Standardization and quality controls for the methylated DNA immunoprecipitation technique

Lisanti, Sofia, von Zglinicki, Thomas, Mathers, John C.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.25 MB

english, 2012

96

Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays

Miwa, Satomi, Treumann, Achim, Bell, Amy, Vistoli, Giulio, Nelson, Glyn, Hay, Sam, von Zglinicki, Thomas

Journal:

Free Radical Biology and Medicine

Year:

2016

Language:

english

File:

PDF, 3.70 MB

english, 2016

97

Shifting focus

Nelson, Glyn, von Zglinicki, Thomas

Journal:

Year:

2010

Language:

english

File:

PDF, 640 KB

english, 2010

98

DNA damage foci in mitosis are devoid of 53BP1

Nelson, Glyn, Buhmann, Matthias, von Zglinicki, Thomas

Journal:

Year:

2009

Language:

english

File:

PDF, 1.13 MB

english, 2009

99

Extended lifespan and long telomeres in rectal fibroblasts from late-onset ulcerative colitis patients

Getliffe, Katherine M., Martin Ruiz, Carmen, Passos, Jo??o F., von Zglinicki, Thomas, Nwokolo, Chuka U.

Journal:

European Journal of Gastroenterology & Hepatology

Year:

2006

Language:

english

File:

PDF, 136 KB

english, 2006

100

Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921

Harris, Sarah E., Marioni, Riccardo E., Martin-Ruiz, Carmen, Pattie, Alison, Gow, Alan J., Cox, Simon R., Corley, Janie, von Zglinicki, Thomas, Starr, John M., Deary, Ian J.

Journal:

Mechanisms of Ageing and Development

Year:

2016

Language:

english

File:

PDF, 796 KB

english, 2016