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Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for ‘ping pong’ kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione
Gavin McManus, Marta Costa, Albert Canals, Miquel Coll, Timothy J. MantleVolume:
278
Year:
2011
Language:
english
Pages:
9
DOI:
10.1111/j.1742-4658.2010.07944.x
File:
PDF, 555 KB
english, 2011