Adoptive immunotherapy with genetically engineered T cells: modification of the IgG1 Fc ‘spacer’ domain in the extracellular moiety of chimeric antigen receptors avoids ‘off-target’ activation and unintended initiation of an innate immune response
Hombach, A, Hombach, A A, Abken, HVolume:
17
Year:
2010
Language:
english
Pages:
8
DOI:
10.1038/gt.2010.91
File:
PDF, 590 KB
english, 2010