A small molecule focal adhesion kinase (FAK) inhibitor, targeting Y397 site: 1-(2-hydroxyethyl) -3, 5, 7-triaza-1-azoniatricyclo [3.3.1.13,7]decane; bromide effectively inhibits FAK autophosphorylation activity and decreases cancer cell viability, clonogenicity and tumor growth in vivo
Ho, B. T., Johnson, C. P., Yemma, M., Huang, G., Zheng, M., Nyberg, C., Magis, A., Ostrov, D. A., Golubovskaya, V. M., Figel, S.Volume:
33
Year:
2012
Language:
english
Pages:
10
DOI:
10.1093/carcin/bgs120
File:
PDF, 971 KB
english, 2012