Discovery and Optimization of a Novel Spiropyrrolidine...

Journal of Medicinal Chemistry 2012 / 11 Vol. 55; Iss. 21

Discovery and Optimization of a Novel Spiropyrrolidine Inhibitor of β-Secretase (BACE1) through Fragment-Based Drug Design

Efremov, Ivan V., Vajdos, Felix F., Borzilleri, Kris A., Capetta, Steven, Chen, Hou, Dorff, Peter H., Dutra, Jason K., Goldstein, Steven W., Mansour, Mahmoud, McColl, Alexander, Noell, Stephen, Oborsk
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Volume:
55
Language:
english
Pages:
20
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm201715d
Date:
November, 2012
File:
PDF, 3.34 MB
english, 2012
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