Discovery of Two Clinical Histamine H 3 Receptor Antagonists: trans - N -Ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) and trans -3-Fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]- N -(2-methylpropyl)cyclobutanecarboxamide (PF-03654764)
Wager, Travis T., Pettersen, Betty A., Schmidt, Anne W., Spracklin, Douglas K., Mente, Scot, Butler, Todd W., Howard, Harry, Lettiere, Daniel J., Rubitski, David M., Wong, Diane F., Nedza, Frank M., NVolume:
54
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm200939b
Date:
November, 2011
File:
PDF, 3.59 MB
english, 2011
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