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Discovery, Synthesis, And Structure-Based Optimization of a Series of N -( tert -Butyl)-2-( N -arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 3CL Protease
Jacobs, Jon, Grum-Tokars, Valerie, Zhou, Ya, Turlington, Mark, Saldanha, S. Adrian, Chase, Peter, Eggler, Aimee, Dawson, Eric S., Baez-Santos, Yahira M., Tomar, Sakshi, Mielech, Anna M., Baker, SusanVolume:
56
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm301580n
Date:
January, 2013
File:
PDF, 3.74 MB
english, 2013