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NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions
Feeney, James, Birdsall, Berry, Kovalevskaya, Nadezhda V., Smurnyy, Yegor. D., Navarro Peran, Emna M., Polshakov, Vladimir I.Volume:
50
Language:
english
Journal:
Biochemistry
DOI:
10.1021/bi200067t
Date:
May, 2011
File:
PDF, 3.21 MB
english, 2011