Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR...

Bioorganic & Medicinal Chemistry 2012 Vol. 20; Iss. 20

Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: Improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacy

Youichi Kawakita, Kazuhiro Miwa, Masaki Seto, Hiroshi Banno, Yoshikazu Ohta, Toshiya Tamura, Tadashi Yusa, Hiroshi Miki, Hidenori Kamiguchi, Yukihiro Ikeda, Toshimasa Tanaka, Keiji Kamiyama, Tomoyasu
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Volume:
20
Year:
2012
Language:
english
DOI:
10.1016/j.bmc.2012.08.002
File:
PDF, 681 KB
english, 2012
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