Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial
Matthew R Sydes, Mahesh KB Parmar, Malcolm D Mason, Noel W Clarke, Claire Amos, John Anderson, Johann de Bono, David P Dearnaley, John Dwyer, Charlene Green, Gordana Jovic, Alastair WS Ritchie, J MartVolume:
13
Language:
english
DOI:
10.1186/1745-6215-13-168
Date:
December, 2012
File:
PDF, 323 KB
english, 2012