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Synthesis and evaluation of .alpha.-[[(2-haloethyl)amino]methyl]-2-nitro-1H-imidazole-1-ethanols as prodrugs of .alpha.-[(1-aziridinyl)methyl]-2-nitro-1H-imidazole-1-ethanol (RSU-1069) and its analogs which are radiosensitizers and bioreductively activated cytotoxins
Jenkins, Terence C., Naylor, Matthew A., O'Neill, Peter, Threadgill, Michael D., Cole, Shirley, Stratford, Ian J., Adams, Gerald E., Fielden, E. Martin, Suto, Mark J., Stier, Michael A.Volume:
33
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm00171a040
Date:
September, 1990
File:
PDF, 1.11 MB
english, 1990