The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD + ) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition
Zhao, Xun, Allison, Dagart, Condon, Bradley, Zhang, Feiyu, Gheyi, Tarun, Zhang, Aiping, Ashok, Sheela, Russell, Marijane, MacEwan, Iain, Qian, Yuewei, Jamison, James A., Luz, John GatelyVolume:
56
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm301431y
Date:
February, 2013
File:
PDF, 3.96 MB
english, 2013