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Synthesis and optimization of novel (3S,5R)-5-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)piperidine-3-carboxamides as orally active renin inhibitors
Mori, Yutaka, Ogawa, Yasuyuki, Mochizuki, Akiyoshi, Nakamura, Yuji, Fujimoto, Teppei, Sugita, Chie, Miyazaki, Shojiro, Tamaki, Kazuhiko, Nagayama, Takahiro, Nagai, Yoko, Inoue, Shin-ichi, Chiba, KatsuVolume:
21
Language:
english
Journal:
Bioorganic & Medicinal Chemistry
DOI:
10.1016/j.bmc.2013.06.057
Date:
September, 2013
File:
PDF, 665 KB
english, 2013