Discovery and Evaluation of 4-(2-(4-chloro-1...

Journal of Medicinal Chemistry 2008 / 10 Vol. 51; Iss. 19

Discovery and Evaluation of 4-(2-(4-chloro-1 H -pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1 H -benzo[ d ]imidazol-2-yl)pyridin-2(1 H )-one (BMS-695735), an Orally Efficacious Inhibitor of Insulin-like Growth Factor-1 Receptor Kinase with Broad Spectrum in Vivo Antitumor Activity

Velaparthi, Upender, Wittman, Mark, Liu, Peiying, Carboni, Joan M., Lee, Francis Y., Attar, Ricardo, Balimane, Praveen, Clarke, Wendy, Sinz, Michael W., Hurlburt, Warren, Patel, Karishma, Discenza, Lo
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Volume:
51
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm800832q
Date:
October, 2008
File:
PDF, 205 KB
english, 2008
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