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Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response to NAC
Chandan Verma, Jennifer M Eremin, Adrian Robins…Volume:
11
Language:
english
DOI:
10.1186/1479-5876-11-16
Date:
December, 2013
File:
PDF, 592 KB
english, 2013