Cyclic Hydroxyamidines as Amide Isosteres: Discovery of Oxadiazolines and Oxadiazines as Potent and Highly Efficacious γ-Secretase Modulators in Vivo
Sun, Zhong-Yue, Asberom, Theodros, Bara, Thomas, Bennett, Chad, Burnett, Duane, Chu, Inhou, Clader, John, Cohen-Williams, Mary, Cole, David, Czarniecki, Michael, Durkin, James, Gallo, Gioconda, GreenlVolume:
55
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm201407j
Date:
January, 2012
File:
PDF, 1.46 MB
english, 2012