Strategic use of conformational bias and structure based...

Bioorganic & Medicinal Chemistry Letters 2013 / 05 Vol. 23; Iss. 9

Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome

Lynch, Stephen M., DeVicente, Javier, Hermann, Johannes C., Jaime-Figueroa, Saul, Jin, Sue, Kuglstatter, Andreas, Li, Hongju, Lovey, Allen, Menke, John, Niu, Linghao, Patel, Vaishali, Roy, Douglas, So
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Volume:
23
Language:
english
Journal:
Bioorganic & Medicinal Chemistry Letters
DOI:
10.1016/j.bmcl.2013.02.012
Date:
May, 2013
File:
PDF, 3.07 MB
english, 2013
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