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Binding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis studies: Application of the ‘message–address’ concept in development of mu opioid receptor selective antagonists
Zaidi, Saheem A., Arnatt, Christopher K., He, Hengjun, Selley, Dana E., Mosier, Philip D., Kellogg, Glen E., Zhang, YanVolume:
21
Language:
english
Journal:
Bioorganic & Medicinal Chemistry
DOI:
10.1016/j.bmc.2013.08.042
Date:
November, 2013
File:
PDF, 3.61 MB
english, 2013