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Pyrrole-imidazole polyamide, a synthetic DNA-binding compound, is effective at increasing levels of wild-type mtDNA in both cybrid cells and MELAS patient-derived fibroblast cells with the MELAS A3243G mutation by a selective promotion of wild-type replication
Yano, Takamitsu, Takeuchi-Tomita, Nono, Ueda, Takuya, Haas, Richard H.Volume:
13
Language:
english
Journal:
Mitochondrion
DOI:
10.1016/j.mito.2013.07.070
Date:
November, 2013
File:
PDF, 61 KB
english, 2013