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In vitro and in vivo pharmacological profile of PL-3994, a novel cyclic peptide (Hept-cyclo(Cys-His-Phe-d-Ala-Gly-Arg-d-Nle-Asp-Arg-Ile-Ser-Cys)-Tyr-[Arg mimetic]-NH2) natriuretic peptide receptor-A agonist that is resistant to neutral endopeptidase and acts as a bronchodilator
Edelson, Jeffrey D., Makhlina, Marie, Silvester, Kevin R., Vengurlekar, Shailesh S., Chen, Xiaomei, Zhang, Jie, Koziol-White, Cynthia J., Cooper, Philip R., Hallam, Trevor J., Hay, Douglas W.P., PanetVolume:
26
Language:
english
Journal:
Pulmonary Pharmacology & Therapeutics
DOI:
10.1016/j.pupt.2012.11.001
Date:
April, 2013
File:
PDF, 688 KB
english, 2013