P-950 Combined antisense chemoradioimmunotherapy consistingof anti-HER2 scFv linked onto high energy radioisotopes, vinorelbine and 21-nucleotide double stranded siRNA targeted to DNMT1 induce PCD in metastatic NSCLC characterised by hypermethylated oncosuppressor p16 promoter CpG islands and overexpression of oncogenes cdc25c, Raf-1, HER-2 and bcl-2

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