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Design and Synthesis of 2- and 3-Substituted-3-phenylpropyl Analogs of 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine: Role of Amino, Fluoro, Hydroxyl, Methoxyl, Methyl, Methylene, and Oxo Substituents on Affinity for the Dopamine and Serotonin Transporters
Hsin, Ling-Wei, Chang, Li-Te, Rothman, Richard B., Dersch, Christina M., Jacobson, Arthur E., Rice, Kenner C.Volume:
51
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm701270n
Date:
May, 2008
File:
PDF, 234 KB
english, 2008