Highly Dissociative and Concerted Mechanism for the Nicotinamide Cleavage Reaction in Sir2Tm Enzyme Suggested by Ab Initio QM/MM Molecular Dynamics Simulations
Hu, Po, Wang, Shenglong, Zhang, YingkaiVolume:
130
Language:
english
Journal:
Journal of the American Chemical Society
DOI:
10.1021/ja807269j
Date:
December, 2008
File:
PDF, 2.13 MB
english, 2008