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Discovery of Clinical Candidate 1-(4-(3-(4-(1 H -Benzo[ d ]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), A Potent, Selective, and Efficacious Inhibitor of Phosphodiesterase 10A (PDE10A)
Hu, Essa, Chen, Ning, Bourbeau, Matthew P., Harrington, Paul E., Biswas, Kaustav, Kunz, Roxanne K., Andrews, Kristin L., Chmait, Samer, Zhao, Xiaoning, Davis, Carl, Ma, Ji, Shi, Jianxia, Lester-ZeinerVolume:
57
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm500713j
Date:
August, 2014
File:
PDF, 2.19 MB
english, 2014