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Fine Tuning of Electrostatics around the Internucleotidic Phosphate through Incorporation of Modified 2′,4′-Carbocyclic-LNAs and -ENAs Leads to Significant Modulation of Antisense Properties
Zhou, Chuanzheng, Liu, Yi, Andaloussi, Mounir, Badgujar, Naresh, Plashkevych, Oleksandr, Chattopadhyaya, JyotiVolume:
74
Language:
english
Journal:
The Journal of Organic Chemistry
DOI:
10.1021/jo8016742
Date:
January, 2009
File:
PDF, 5.09 MB
english, 2009