A Sorbitol Dehydrogenase Inhibitor of Exceptional in Vivo Potency with a Long Duration of Action:  1-( R )-{4-[4-(4,6-Dimethyl[1,3,5]triazin-2-yl)- 2 R ,6 S -dimethylpiperazin-1-yl]pyrimidin-2- yl}ethanol

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