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Elimination of a good leaving group from the 3'-position of a cephalosporin need not be concerted with .beta.-lactam ring opening: TEM-2 .beta.-lactamase-catalyzed hydrolysis of pyridine-2-azo-4'-(N',N'-dimethylaniline) cephalosporin (PADAC) and of cephaloridine
Faraci, W. Stephen, Pratt, R. F.Volume:
106
Language:
english
Journal:
Journal of the American Chemical Society
DOI:
10.1021/ja00317a053
Date:
March, 1984
File:
PDF, 261 KB
english, 1984