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Reaction Development and Mechanistic Study of a Ruthenium Catalyzed Intramolecular Asymmetric Reductive Amination en Route to the Dual Orexin Inhibitor Suvorexant (MK-4305)
Strotman, Neil A., Baxter, Carl A., Brands, Karel M. J., Cleator, Ed, Krska, Shane W., Reamer, Robert A., Wallace, Debra J., Wright, Timothy J.Volume:
133
Language:
english
Journal:
Journal of the American Chemical Society
DOI:
10.1021/ja202358f
Date:
June, 2011
File:
PDF, 1.24 MB
english, 2011