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Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-thienylmethyl)-4H-pyrrolo[3,2-d]pyrimidin-4-one (CI-972)
Sircar, Jagadish C., Kostlan, Catherine R., Gilbertsen, Richard B., Bennett, Mary K., Dong, Mi K., Cetenko, W. J.Volume:
35
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm00087a015
Date:
May, 1992
File:
PDF, 706 KB
english, 1992