Inhibitors of β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1): Identification of ( S )-7-(2-Fluoropyridin-3-yl)-3-((3-methyloxetan-3-yl)ethynyl)-5′ H -spiro[chromeno[2,3- b ]pyridine-5,4′-oxazol]-2′-amine (AMG-8718)
Dineen, Thomas A., Chen, Kui, Cheng, Alan C., Derakhchan, Katayoun, Epstein, Oleg, Esmay, Joel, Hickman, Dean, Kreiman, Chuck E., Marx, Isaac E., Wahl, Robert C., Wen, Paul H., Weiss, Matthew M., WhitVolume:
57
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm5012676
Date:
December, 2014
File:
PDF, 2.09 MB
english, 2014