Finding the perfect spot for fluorine: Improving potency up to 40-fold during a rational fluorine scan of a Bruton’s Tyrosine Kinase (BTK) inhibitor scaffold
Lou, Yan, Sweeney, Zachary K., Kuglstatter, Andreas, Davis, Dana, Goldstein, David M., Han, Xiaochun, Hong, Junbae, Kocer, Buelent, Kondru, Rama K., Litman, Renee, McIntosh, Joel, Sarma, Keshab, Suh,Volume:
25
Language:
english
Journal:
Bioorganic & Medicinal Chemistry Letters
DOI:
10.1016/j.bmcl.2014.11.030
Date:
January, 2015
File:
PDF, 1.02 MB
english, 2015
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