Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran-3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)
Hwei-Ru Tsou, Gloria MacEwan, Gary Birnberg, George Grosu, Matthew G. Bursavich, Joel Bard, Natasja Brooijmans, Lourdes Toral-Barza, Irwin Hollander, Tarek S. Mansour, Semiramis Ayral-Kaloustian, KerVolume:
20
Year:
2010
Language:
english
Pages:
5
DOI:
10.1016/j.bmcl.2010.01.135
File:
PDF, 1.24 MB
english, 2010