A new structural alert for benzimidazoles:...

Bioorganic & Medicinal Chemistry Letters 2011 Vol. 21; Iss. 5

A new structural alert for benzimidazoles: 2,6-Dimethylphenyl substituents increase mutagenic potential and time-dependent CYP3A4 inhibition risk

Youngshin Kwak, Gary Coppola, Cornelia J. Forster, Thomas A. Gilmore, Yongjin Gong, Aaron Kanter, Alan Neubert, Bryan Stroup, Paul Szklennik, Susanne Glowienke, Pascal Stadelmann, Leslie Bell, Shari B
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Volume:
21
Year:
2011
Language:
english
Pages:
3
DOI:
10.1016/j.bmcl.2011.01.023
File:
PDF, 382 KB
english, 2011
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