Age-dependent Accumulation of Soluble Amyloid (A ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein- (sAPP ) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3 Pathway in Alzheimer Mouse Model
Jimenez, S., Torres, M., Vizuete, M., Sanchez-Varo, R., Sanchez-Mejias, E., Trujillo-Estrada, L., Carmona-Cuenca, I., Caballero, C., Ruano, D., Gutierrez, A., Vitorica, J.Volume:
286
Language:
english
Journal:
Journal of Biological Chemistry
DOI:
10.1074/jbc.m110.209718
Date:
May, 2011
File:
PDF, 3.77 MB
english, 2011