Multi-parameter optimization of aza-follow-ups to BI...

Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity

Beaulieu, Pierre L., Bolger, Gordon, Deon, Dan, Duplessis, Martin, Fazal, Gulrez, Gagnon, Alexandre, Garneau, Michel, LaPlante, Steven, Stammers, Timothy, Kukolj, George, Duan, Jianmin
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Volume:
25
Language:
english
Journal:
Bioorganic & Medicinal Chemistry Letters
DOI:
10.1016/j.bmcl.2014.12.078
Date:
March, 2015
File:
PDF, 376 KB
english, 2015
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