Synthesis, SAR, and Series Evolution of Novel...

Synthesis, SAR, and Series Evolution of Novel Oxadiazole-Containing 5-Lipoxygenase Activating Protein Inhibitors: Discovery of 2-[4-(3-{( R )-1-[4-(2-Amino-pyrimidin-5-yl)-phenyl]-1-cyclopropyl-ethyl}-[1,2,4]oxadiazol-5-yl)-pyrazol-1-yl]- N , N -dimethyl-acetamide (BI 665915)

Takahashi, Hidenori, Riether, Doris, Bartolozzi, Alessandra, Bosanac, Todd, Berger, Valentina, Binetti, Ralph, Broadwater, John, Chen, Zhidong, Crux, Rebecca, De Lombaert, Stéphane, Dave, Rajvee, Dine
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Volume:
58
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm501185j
Date:
February, 2015
File:
PDF, 932 KB
english, 2015
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