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Predictive Dose-Based Estimation of Systemic Exposure Multiples in Mouse and Monkey Relative to Human for Antisense Oligonucleotides With 2′-O-(2-Methoxyethyl) Modifications
Yu, Rosie Z, Grundy, John S, Henry, Scott P, Kim, Tae-Won, Norris, Daniel A, Burkey, Jennifer, Wang, Yanfeng, Vick, Andrew, Geary, Richard SVolume:
4
Language:
english
Journal:
Molecular Therapy—Nucleic Acids
DOI:
10.1038/mtna.2014.69
Date:
January, 2015
File:
PDF, 542 KB
english, 2015