Enantiomers of HA-966 (3-Amino-1-Hydroxypyrrolid-2-One)...

Enantiomers of HA-966 (3-Amino-1-Hydroxypyrrolid-2-One) Exhibit Distinct Central Nervous System Effects: (+)-HA-966 is a Selective Glycine/N- Methyl-D-Aspartate Receptor Antagonist, But (-)-HA-966 is a Potent γ-Butyrolactone-Like Sedative

L. Singh, A. E. Donald, A. C. Foster, P. H. Hutson, L. L. Iversen, S. D. Iversen, J. A. Kemp, P. D. Leeson, G. R. Marshall, R. J. Oles, T. Priestley, L. Thorn, M. D. Tricklebank, C. A. Vass and B. J.
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Volume:
87
Language:
english
Journal:
Proceedings of the National Academy of Sciences of the United States of America
DOI:
10.2307/2353688
Date:
April, 1990
File:
PDF, 1.23 MB
english, 1990
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