An Inhibitory Metabolite Leads to Dose- and Time-Dependent...

Drug Metabolism and Disposition 2009 / 03 Vol. 37; Iss. 3

An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N- -N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing

Tonn, G. R., Wong, S. G., Wong, S. C., Johnson, M. G., Ma, J., Cho, R., Floren, L. C., Kersey, K., Berry, K., Marcus, A. P., Wang, X., Van Lengerich, B., Medina, J. C., Pearson, P. G., Wong, B. K.
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Volume:
37
Language:
english
Journal:
Drug Metabolism and Disposition
DOI:
10.1124/dmd.108.021931
Date:
March, 2009
File:
PDF, 525 KB
english, 2009
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