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I1171 missense mutation (particularly I1171N) is a common resistance mutation in ALK-positive NSCLC patients who have progressive disease while on alectinib and is sensitive to ceritinib
Ou, Sai-Hong Ignatius, Greenbowe, Joel, Khan, Ziad U., Azada, Michele C., Ross, Jeffrey S., Stevens, Phil J., Ali, Siraj M., Miller, Vincent A., Gitlitz, BarbaraVolume:
88
Language:
english
Journal:
Lung Cancer
DOI:
10.1016/j.lungcan.2015.02.005
Date:
May, 2015
File:
PDF, 1.08 MB
english, 2015