Improving the Pharmacokinetic and CYP Inhibition Profiles of Azaxanthene-Based Glucocorticoid Receptor Modulators—Identification of ( S )-5-(2-(9-Fluoro-2-(4-(2-hydroxypropan-2-yl)phenyl)-5 H -chromeno[2,3- b ]pyridin-5-yl)-2-methylpropanamido)- N -(tetrahydro-2 H -pyran-4-yl)-1,3,4-thiadiazole-2-carboxamide (BMS-341)
Yang, Michael G., Dhar, T. G. Murali, Xiao, Zili, Xiao, Hai-Yun, Duan, James J.-W., Jiang, Bin, Galella, Michael A., Cunningham, Mark, Wang, Jinhong, Habte, Sium, Shuster, David, McIntyre, Kim W., CarVolume:
58
Language:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.5b00257
Date:
May, 2015
File:
PDF, 1.11 MB
english, 2015
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