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Engineering the Specificity of Antibacterial Fluoroquinolones: Benzenesulfonamide Modifications at C-7 of Ciprofloxacin Change Its Primary Target in Streptococcus pneumoniae from Topoisomerase IV to Gyrase
Alovero, F. L., Pan, X.-S., Morris, J. E., Manzo, R. H., Fisher, L. M.Volume:
44
Language:
english
Journal:
Antimicrobial Agents and Chemotherapy
DOI:
10.1128/AAC.44.2.320-325.2000
Date:
February, 2000
File:
PDF, 584 KB
english, 2000