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Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
REDFERN, W, CARLSSON, L, DAVIS, A, LYNCH, W, MACKENZIE, I, PALETHORPE, S, SIEGL, P, STRANG, I, SULLIVAN, A, WALLIS, RVolume:
58
Language:
english
Journal:
Cardiovascular Research
DOI:
10.1016/s0008-6363(02)00846-5
Date:
April, 2003
File:
PDF, 713 KB
english, 2003