Characterization of Binding Mode of Action of a Blocking...

Biochemistry 2015 / 03 Vol. 54; Iss. 10

Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-β

Kuai, Jun, Mosyak, Lidia, Brooks, Jon, Cain, Michael, Carven, Gregory J., Ogawa, Shinji, Ishino, Tetsuya, Tam, May, Lavallie, Edward R., Yang, Zhiyong, Ponsel, Dirk, Rauchenberger, Robert, Arch, Rober
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Volume:
54
Language:
english
Journal:
Biochemistry
DOI:
10.1021/bi5015425
Date:
March, 2015
File:
PDF, 7.51 MB
english, 2015
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