Biotransformation of a Novel Positive Allosteric Modulator...

Drug Metabolism and Disposition 2013 / 09 Vol. 41; Iss. 9

Biotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent Mechanism

Bridges, T. M., Rook, J. M., Noetzel, M. J., Morrison, R. D., Zhou, Y., Gogliotti, R. D., Vinson, P. N., Xiang, Z., Jones, C. K., Niswender, C. M., Lindsley, C. W., Stauffer, S. R., Conn, P. J., Danie
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Volume:
41
Language:
english
Journal:
Drug Metabolism and Disposition
DOI:
10.1124/dmd.113.052084
Date:
September, 2013
File:
PDF, 540 KB
english, 2013
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