Resistance to dual blockade of the kinases PI3K and mTOR in...

Science Signaling 2014 / 11 Vol. 7; Iss. 351

Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR

Belmont, P. J., Jiang, P., McKee, T. D., Xie, T., Isaacson, J., Baryla, N. E., Roper, J., Sinnamon, M. J., Lee, N. V., Kan, J. L. C., Guicherit, O., Wouters, B. G., O'Brien, C. A., Shields, D., Olson,
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Volume:
7
Language:
english
Journal:
Science Signaling
DOI:
10.1126/scisignal.2005516
Date:
November, 2014
File:
PDF, 921 KB
english, 2014
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