Synthesis of 4-Substituted Phthalazin-1(2 H...

Organic Process Research & Development 2015 / 07 Vol. 19; Iss. 7

Synthesis of 4-Substituted Phthalazin-1(2 H )-ones from 2-Acylbenzoic Acids: Controlling Hydrazine in a Pharmaceutical Intermediate through PAT-Guided Process Development

Mennen, Steven M., Mak-Jurkauskas, Melody L., Bio, Matthew M., Hollis, L. Steven, Nadeau, Kelly A., Clausen, Andrew M., Hansen, Karl B.
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Volume:
19
Language:
english
Journal:
Organic Process Research & Development
DOI:
10.1021/acs.oprd.5b00135
Date:
July, 2015
File:
PDF, 2.50 MB
english, 2015
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