Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia
Dong, Qian, Ernst, Sarah E., Ostedgaard, Lynda S., Shah, Viral S., Ver Heul, Amanda R., Welsh, Michael J., Randak, Christoph O.Volume:
290
Language:
english
Journal:
Journal of Biological Chemistry
DOI:
10.1074/jbc.m114.611616
Date:
May, 2015
File:
PDF, 3.47 MB
english, 2015